Anavar (oxandrolone)

Anavar (oxandrolone)

Anavar has a reputation for being a “safe steroid” especially for women.

Anavar is the original brand name for the orally-active anabolic steroid oxandrolone. Although oxandrolone has been marketed by several other brand names over the past 50+ years, athletes continue to refer to oxandrolone as Anavar.

Anavar was commercially introduced by the American pharmaceutical company G.D. Searle in 1964. It was one of the first orally-active anabolic steroids synthesized. Anavar joined Dianabol, Anadrol and Nilevar as popular oral steroid options for curious bodybuilders at the time.

Anavar has fewer side effects than other steroids.

Anavar distinguished itself among other oral steroids as being much safer with fewer side effects. It displayed six times the anabolic activity of testosterone with far less androgenic activity than testosterone in assays.

Anavar is a C17-alpha alkylated anabolic steroid like most other oral steroids. This chemical alteration to the compound prevents it from being deactivated by the liver. It also introduces a certain amount of liver stress or hepatoxicity.

The good news is that Anavar causes notably less hepatoxicity than other C17-alpha alkylated steroids metabolized by the liver.

Anavar is a non-aromatizing steroid whereas it does not show any estrogenic activity or related progestagenic activity. It does not convert to dihydrotestosterone (DHT) either.

For all of the aforementioned reasons, Anavar has fewer and less severe side effects than most other steroids. This has made it one of the most popular steroids for women, newbies and excessively cautious men.

Conservative steroid users may choose Anavar for its favorable safety profile. The choice of Anavar seems like good alternative to steroids that show a propensity to cause water retention, oily skin, and even gynecomastia due to the their conversion to estradiol and/or DHT.

These side effects can be avoided with Anavar-only cycles. Anavar simply does not metabilize at all into E2 or DHT. Other oral steroids like Dianabol do.

Anavar has a negative impact on natural testosterone production and lipid profile — like most other steroids.

Anavar may be an extremely mild steroid in terms of overt adverse side effects but this does not mean it is free of all side effects that accompany steroid use. Some side effects are unavoidable when it comes to drugs that act on the androgen receptor.

It should be strongly noted that Anavar, like all anabolic steroids and selective androgen receptor (SARMs), suppresses the natural production of testosterone to some degree. Many websites suggest that the suppressive effects of Anavar are trivial but this is incorrect.

In addition, Anavar also has adverse effects on blood lipids. Many bodybuilders are surprised by the pronounced effect that oral steroids like Anavar can have on their cholesterol levels. In particular, the decrease in HDL levels can be dramatic and quite disconcerting.

Liver toxicity of Anavar.

The liver toxicity of Anavar also make it an ill-advised and unsuitable choice for a lengthy high-dosed oral cycle. As a general rule, oral steroids like Anavar should not be used more than 4-6 weeks continuously to avoid potential liver problems.

All things considered, Anavar remains the top choice of steroids for women and overly-cautious men (especially those afraid of needles). However, there are important things that both groups should know.

Anavar for men.

Most men who use Anavar will be greatly disappointed in the results. The side effects may be mild but so are the results in terms of strength and muscle gain.

The results can be improved somewhat by escalating the dosage to 100-150 milligrams per day. But most men who choose Anavar are too fearful of side effects to use much more than 20-50 milligrams.

Anavar is definitely not useless for men. It may be overrated and overpriced. But it can be a useful steroids just not as a standalone drug protocol.

Anavar used in combination with various other anabolic steroids, particularly injectable steroids, can have additive and even synergistic effects when combined intelligently.

Anavar for women.

Women who use Anavar based on the common belief that it is non- or minimally virilizing may walk away disappointed. The potentially masculinizing side effects of Anavar may be less than that of most other steroids but they still exist.

Such undesirable side effects, particularly changes in voice and/or increased facial or body hair, for women are not unusual at dosages of 20 milligrams per day.

While many women can avoid these side effects with short-term daily dosages of only 5 to 10 mg/day, some women will not be so lucky.

An added benefit of Anavar that many women may find welcome and desirable is the drug’s effect on libido. Anavar can also result in temporary or even permanent clitoral enlargement which can have pro-sexual advantages that persist long after discontinuation.

The quality of the product is another extremely important consideration for women who want to use Anavar. There is always the chance that a women will unwittingly purchase and consume an Anavar product that actually contains a more virilizing oral steroid like Dianabol or Winstrol.

This would represent a nightmare scenario for a women who expected to use 10 mg/tablet of Anavar but was actually using 10 mg/tablet of Dianabol. This amount of Dianabol is very androgenic and would most certainly result is some virilizing effects over the course of a cycle.

Given that most anabolic steroids used by bodybuilders are obtained via the Internet black market, the likelihood of buying pharmaceutical-quality is next to zero. Most black market steroids are manufactured by clandestine underground laboratories (UGLs) that are not subject to government regulation.

Women are advised to have their Anavar analyzed for content.

Fortunately, there are several analytical lab testing services that can analyze anabolic steroid products to verify their ingredients.

The analytical lab testing services are not free but they can provide a guarantee of both the ingredients and their concentration.

Verifying that an Anavar product contains oxandrolone is not enough for women users. The dosage concentration is equally important.

Analytical testing can cost between $100 and $300 depending on the analytical laboratory used. In many cases, the costs of testing may exceed the cost of the actual product itself.

Nonetheless, this additional cost would represent a wise investment for a women who chooses to use anabolic steroids. Given that the masculinizing side effects could be somewhat permanent, it is best to take every precaution in order to avoid any additional risk.

Women can’t eliminate all the risks associated with Anavar, particularly the virilizing effects. But at the very least, they can guarantee they are actually receiving Anavar.

Anavar by Gen-Shi Labs PHOTO

Anavar by Gen-Shi Labs PHOTO

  • Llewellyn, W. (2009). Anabolics, 9th Edition. Molecular Nutrition: Jupiter, Florida.

  • Roberts, B. (2015). Anavar Profile. Retrieved from

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